That year, he directed his second film El camino de los ingleses, based on the novel by Antonio Soler and also received the L. Latino International Film Festival's "Gabi" Lifetime Achievement Award on 14 October.
In 2011, the horror thriller The Skin I Live In marked the return of Banderas to Pedro Almodóvar, the Spanish director who launched his international career. In The Skin I Live In he breaks out of the "Latin Lover" mold from his Hollywood work and stars as a calculating revenge-seeking plastic surgeon following the rape of his daughter.
Banderas' debut as a director was the poorly received Crazy in Alabama (1999), starring his then wife Melanie Griffith.In 2003, he returned to the musical genre, appearing to great acclaim in the Broadway revival of Maury Yeston's musical Nine, based on the film 8½, playing the prime role originated by Raul Julia.As a child, he wanted to become a professional football player until a broken foot sidelined his dreams at the age of fourteen.He showed a strong interest in the performing arts and formed part of the ARA Theatre-School run by Ángeles Rubio-Argüelles y Alessandri (wife of diplomat, writer and film director Edgar Neville) and the College of Dramatic Art, both in Málaga.Five years later, he went on to appear in the director's Law of Desire, making headlines with his performance as a gay man, which required him to engage in his first male-to-male onscreen kiss.
After Banderas appeared in Almodóvar's 1986 Matador, the director cast him in his internationally acclaimed 1988 film, Women on the Verge of a Nervous Breakdown. Despite having to learn all his lines phonetically, Banderas still managed to turn in a critically praised performance as a struggling musician in his first American drama film, The Mambo Kings (1992).
In 1996, Banderas appeared among other figures of Spanish culture in a video supporting the Spanish Socialist Workers' Party lists in the general election.
In 2013, he called on Europe and the United States to emulate Hugo Chávez in Venezuela and nationalize big corporations as a solution to the global economic crisis.
After the success of Antonio for Men and Blue Seduction for Men in 2007, launched his latest Blue Seduction for Women the following year.
Banderas received an honorary degree from Dickinson College in 2000.
He owns 50% of a winery in Villalba de Duero, Burgos, Spain, called Anta Banderas, which produces red and rosé wines. The actor has been working with fragrance and beauty multinational company Puig for over ten years becoming one of the brand's most successful representatives.